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Role of innate immune cells

We are also actively investigating the contribution of different innate immune cells, such as alveolar macrophages, monocytes, neutrophils and dendritic cells in respiratory infection. We are currently utilizing a range of mouse genetic models to better understand alveolar macrophage development and function in the airway. These specific knockout mice will be used to better understand how these cells develop and the various roles they play in different insult scenarios.

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